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Sulfur Fumigation Processing of Traditional Chinese Medicinal Herbs: Beneficial or Detrimental?

机译：中草药的硫熏蒸处理：有益还是有害？

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摘要

Majority of traditional Chinese medicine (TCM) herbs need to undergo post-harvesting processing to convert raw material into the form readily used for prescription. In general, processing procedures are either according to China Pharmacopeia or based on traditional methods. Recently sulfur fumigation is increasingly used to replace traditional sun-drying for its pesticidal and anti-bacterial properties in a cheap and convenient manner. However, to date information on effects of sulfur fumigation on herbal safety and efficacy are limited. This article addresses potential destructive effects of sulfur fumigation on herbal efficacy and safety through reviewing currently available information. Since recently increased numbers of studies have demonstrated that sulfur fumigation-induced dramatic changes in chemical profiles of various sulfur-fumigated herbs, consequent alteration of efficacy, and/or potential incidence of toxicity are suspected. Therefore comprehensive investigations on effects of sulfur fumigation on toxicity, chemical profiles, pharmacokinetics, and bioactivities of TCM herbs are timely to provide scientific basis for standardization and regulation of this currently common but potentially harmful processing method.
机译：多数传统中药（TCM）草药需要进行收获后加工，以将原料转化为易于处方的形式。一般而言，加工程序要么根据《中国药典》进行，要么基于传统方法。近来，硫熏蒸法以其廉价和方便的方式具有杀虫和抗菌性能，越来越多地用于代替传统的日晒。但是，迄今为止，有关硫熏蒸对草药安全性和功效的影响的信息还很有限。本文通过回顾当前可获得的信息，探讨了硫熏蒸对草药功效和安全性的潜在破坏作用。自最近以来，越来越多的研究表明，怀疑有硫熏蒸引起的各种硫熏蒸草药化学特性的急剧变化，功效的改变和/或潜在的毒性发生。因此，对硫熏蒸对中草药毒性，化学特性，药代动力学和生物活性的影响进行全面研究是及时的，从而为标准化和规范这种目前普遍但可能有害的加工方法提供了科学依据。

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